Diuretic Renal Scintigraphy in Patients with Sulfonamide Allergies: Possible Alternative Use of Ethacrynic Acid.

نویسندگان

  • Ba D Nguyen
  • Michael C Roarke
  • Jason Robert Young
  • Ming Yang
  • Howard H Osborn
چکیده

UNLABELLED Furosemide may trigger life-threatening sulfonamide cross-hypersensitivity reactions, posing a dilemma in patients who need diuretic renal scintigraphy. METHODS We present our experience using ethacrynic acid as a nonsulfonamide alternative diuretic in 5 patients, with a discussion of the diuretic molecular structure, potential side effects, protocol development, and imaging results. RESULTS Diuretic renal scintigraphy using ethacrynic acid provided useful information about the obstruction status in all patients, with no adverse clinical impact. CONCLUSION Ethacrynic acid is a potential alternative to furosemide for patients with severe sulfonamide reactions.

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عنوان ژورنال:
  • Journal of nuclear medicine technology

دوره 43 4  شماره 

صفحات  -

تاریخ انتشار 2015